Prostate specific antigen (PSA) - Conjugated


Ornstein DK, Smith DS et al, 1997, J Urol, 157, 2179-82 , Biological variation of total, free and percent free serumm protate specific antigen levels in screening volunteers


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand B
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA) - Conjugated
Unit % / %
Overall Analytical Principle Method Immunoassay; Other
Number of Subjects 84
Number of Subjects included in BV estimation 84
Ethinicity Unknown
Age Mean / Median 66.0
Age Min 53.0
Age Max 84.0
Age SD
Number of Males 84
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples
Average Number of Samples Used for BV Estimation 3.0
Average Number of Replicates 1.0
Estimates of CVi 14.0
Calculated Confidence Intervals of CVi Lower: 12.44, Upper: 15.83
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 4.3
Calculated Confidence Intervals of Analytical CV Lower: 3.37, Upper: 5.94
Measurand Mean 25.2
Measurand Min 12.8
Measurand Max 37.6
Measurand SD