Prostate specific antigen (PSA)

Reference

Reference
Christensson A, Bruun L, Björk T et al, 2011, BJU Int, 107, 1769-74 , Intra-individual short-term variability of prostate-specific antigen and other kallikrein markers in a serial collection of blood from men under evaluation for prostate càncer

Scoring

Total Score

C6,7,8,10,11,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis C
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C6,7,8,10,11,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA)
Unit ng / mL
Overall Analytical Principle Method Immunoassay; Time-resolved immunofluorometric assay (TR-IMFA)
Number of Subjects 149
Number of Subjects included in BV estimation 149
Ethinicity Unknown
Age Mean / Median 65.0
Age Min 60.0
Age Max 70.0
Age SD
Number of Males 149
Number of Females 0
State of Well Being
Non-healthy (excl pregnant)
Diseases
Study Duration Length 1
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 7
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 2
Average Number of Samples Used for BV Estimation
Average Number of Replicates 1.0
Estimates of CVi 11.0
Calculated Confidence Intervals of CVi Lower: 9.40, Upper: 12.70
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 5.0
Calculated Confidence Intervals of Analytical CV Lower: 3.98, Upper: 6.72
Measurand Mean 6.6
Measurand Min 4.4
Measurand Max 9.7
Measurand SD

Coding