Prostate specific antigen (PSA)


Ornstein DK, Smith DS et al, 1997, J Urol, 157, 2179-82 , Biological variation of total, free and percent free serumm protate specific antigen levels in screening volunteers


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand B
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA)
Unit ng / mL
Overall Analytical Principle Method Immunoassay; Other
Number of Subjects 23
Number of Subjects included in BV estimation 23
Ethinicity Unknown
Age Mean / Median
Age Min
Age Max
Age SD
Number of Males 23
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples
Average Number of Samples Used for BV Estimation 3.0
Average Number of Replicates 1.0
Estimates of CVi 12.6
Calculated Confidence Intervals of CVi Lower: 8.88, Upper: 16.15
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 4.3
Calculated Confidence Intervals of Analytical CV Lower: 2.77, Upper: 9.47
Measurand Mean
Measurand Min 4.0
Measurand Max
Measurand SD