EFLM Biological Varation Database : BIVAC Minimum Data Set for Prostate specific antigen (PSA) EFLM Biological Variation

Prostate specific antigen (PSA)

Reference

Nixon RG, Wener MH et al, 1997, J Urol, 157, 2183-90 , Biological variation of prostate specific antigen levels In serum: an evaluation of day-to-day physiological fluctuations in a well-defined cohort of 24 patients

Scoring

Total Score

C_7,8,10,11,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	B
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	C
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	C
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_7,8,10,11,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Prostate specific antigen (PSA)
Unit	ng / mL
Overall Analytical Principle Method	Immunoassay; Not specified
Number of Subjects	6
Number of Subjects included in BV estimation	6
Ethinicity	Unknown
Age Mean / Median	71.1
Age Min
Age Max
Age SD
Number of Males	6
Number of Females	0
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	2
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Day
Sampling Times	Start Time: End Time:
Number of Samples	10
Average Number of Samples Used for BV Estimation	9.8
Average Number of Replicates	2.0
Estimates of CVi	5.8
Calculated Confidence Intervals of CVi	Lower: 4.32, Upper: 7.64
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: , Upper:
Analytical CV	5.0
Calculated Confidence Intervals of Analytical CV	Lower: 4.21, Upper: 6.16
Measurand Mean	7.1
Measurand Min
Measurand Max
Measurand SD

Coding

© 2018 - 2019 This website and its content is copyright of EFLM. All rights reserved. Any redistribution or reproduction of part or all of the contents in any form is prohibited other than the following: you may print or download to a local hard disk extracts for your personal and non-commercial use only you may copy the content to individual third parties for their personal use, but only if you acknowledge the website as the source of the material You may not, except with our express written permission, distribute or commercially exploit the content. Nor may you transmit it or store it in any other website or other form of electronic retrieval system.