Prostate specific antigen (PSA)

Reference

Reference
Nixon RG, Wener MH et al, 1997, J Urol, 157, 2183-90 , Biological variation of prostate specific antigen levels In serum: an evaluation of day-to-day physiological fluctuations in a well-defined cohort of 24 patients

Scoring

Total Score

C7,8,10,11,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,11,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA)
Unit ng / mL
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 24
Number of Subjects included in BV estimation 24
Ethinicity Unknown
Age Mean / Median 72.6
Age Min 67.0
Age Max 83.0
Age SD
Number of Males 24
Number of Females 0
State of Well Being
Non-healthy (excl pregnant)
Diseases
Study Duration Length 2
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time:
End Time:
Number of Samples 10
Average Number of Samples Used for BV Estimation 9.8
Average Number of Replicates 2.0
Estimates of CVi 8.8
Calculated Confidence Intervals of CVi Lower: 7.89, Upper: 9.87
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 5.0
Calculated Confidence Intervals of Analytical CV Lower: 4.57, Upper: 5.52
Measurand Mean 6.1
Measurand Min
Measurand Max
Measurand SD

Coding