Prostate specific antigen (PSA)

Reference

Reference
Bruun L, Becker Ch et al, 2005, Prostate, 65, 216-21 , Assessment of intra-individual variation in prostate-specific antigen levels in a biennal randomized prostate càncer screening program in Sweden

Scoring

Total Score

C7,8,10,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical B
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
11. ANOVA B
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA)
Unit ng / mL
Overall Analytical Principle Method Immunoassay; Time-resolved immunofluorometric assay (TR-IMFA)
Number of Subjects 1542
Number of Subjects included in BV estimation 1542
Ethinicity Caucasian
Age Mean / Median
Age Min
Age Max
Age SD
Number of Males 1542
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 8
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 1.0
Estimates of CVi 11.4
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 24.19
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 5.6
Calculated Confidence Intervals of Analytical CV Lower: 5.33, Upper: 5.89
Measurand Mean 0.6
Measurand Min 0.0
Measurand Max 0.99
Measurand SD

Coding