Prostate specific antigen (PSA)


Komatsu K, Wehner N, Prestigiacomo A et al, 1996, Urology, 47(3), 343-6 , Physiologic (intraindividual) variation of serum protate-specific antigen in 814 men from a screening population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical B
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand Prostate specific antigen (PSA)
Unit ng / mL
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 98
Number of Subjects included in BV estimation 98
Ethinicity Unknown
Age Mean / Median
Age Min
Age Max
Age SD
Number of Males 98
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Other
Sampling Times Start Time:
End Time:
Number of Samples 2
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 11.9
Calculated Confidence Intervals of CVi Lower: 10.37, Upper: 13.91
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 2.5
Calculated Confidence Intervals of Analytical CV Lower: 1.90, Upper: 3.65
Measurand Mean
Measurand Min 7.3
Measurand Max 17.9
Measurand SD