Carcinoembryonic antigen (CEA)

Included in meta analysis


Erden G, Barazi AO, Tezcan G and Yildirimkaya MM, 2008, Scand J Clin Lab Invest, 68, 212-8 , Biological variation and reference change vàlues of CA 19-9, CEA, AFP in sèrum of healthy individuals


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Serum
Measurand Carcinoembryonic antigen (CEA)
Unit ug / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 49
Number of Subjects included in BV estimation 43
Ethinicity Unknown
Age Mean / Median 33.1
Age Min 18.0
Age Max 60.0
Age SD 8.7
Number of Males 25
Number of Females 24
State of Well Being
Healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 14
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 10:00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 30.87
Calculated Confidence Intervals of CVi Lower: 27.49, Upper: 35.19
Estimates of CVg 37.14
Calculated Confidence Intervals of CVg Lower: 29.32, Upper: 48.57
Analytical CV 3.8
Calculated Confidence Intervals of Analytical CV Lower: 3.44, Upper: 4.25
Measurand Mean 1.014
Measurand Min 0.54
Measurand Max 1.693
Measurand SD 0.33