Neuron specific enolase

Reference

Reference
Qi Z, Zhang Lin, Chen Y, Ma X et al, 2015, Clin Chim Acta, 450, 233-6 , . Biological variations of seven tumor markers

Scoring

Total Score

C8,10

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
11. ANOVA A
12. CI A
13. No of Results B
14. Concentrations B
15. Total Score C8,10
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Neuron specific enolase
Unit ng / mL
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 20
Number of Subjects included in BV estimation 7
Ethinicity Asian
Age Mean / Median 26.0
Age Min 21.0
Age Max 38.0
Age SD
Number of Males 11
Number of Females 9
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 5
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Hour
Sampling Times Start Time: 08:00
End Time: 16:00
Number of Samples 7
Average Number of Samples Used for BV Estimation 7.0
Average Number of Replicates 2.0
Estimates of CVi 13.2
Calculated Confidence Intervals of CVi Lower: 10.85, Upper: 16.82
Estimates of CVg 16.84
Calculated Confidence Intervals of CVg Lower: 10.42, Upper: 35.40
Analytical CV 2.12
Calculated Confidence Intervals of Analytical CV Lower: 1.77, Upper: 2.64
Measurand Mean 10.8
Measurand Min 5.3
Measurand Max 16.3
Measurand SD

Coding