Included in meta analysis


Bandaranayake N, Ankrah-Tetteh T, Wijeratne S and Swaminathan R, 2007, Clin Chem Lab Med, 45, 1237-9 , Intraindividual variation in creatinine and cystatin C


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Creatinine
Unit micromol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 10
Number of Subjects included in BV estimation 10
Ethinicity Caucasian
Age Mean / Median
Age Min 19.0
Age Max 27.0
Age SD
Number of Males 4
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 42
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 12:30
End Time: 14:30
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 2.0
Estimates of CVi 6.1
Calculated Confidence Intervals of CVi Lower: 5.02, Upper: 7.68
Estimates of CVg 17.4
Calculated Confidence Intervals of CVg Lower: 12.01, Upper: 30.76
Analytical CV 2.3
Calculated Confidence Intervals of Analytical CV Lower: 1.95, Upper: 2.80
Measurand Mean 82.0
Measurand Min
Measurand Max
Measurand SD