Creatinine

Reference

Reference
Rosano TG and Brown HH, 1982, Clin Chem, 28, 2330-1 , Analytical and biological variability of serum creatinine and creatinine clearance: implications for clinical interpretation

Scoring

Total Score

C8,10,11

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C8,10,11
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Creatinine
Unit mg / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 2
Number of Subjects included in BV estimation 2
Ethinicity Caucasian
Age Mean / Median
Age Min 33.0
Age Max 55.0
Age SD
Number of Males 2
Number of Females
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 2
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 24
Average Number of Samples Used for BV Estimation 24.0
Average Number of Replicates 2.0
Estimates of CVi 7.9
Calculated Confidence Intervals of CVi Lower: 5.78, Upper: 10.57
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 6.7
Calculated Confidence Intervals of Analytical CV Lower: 5.59, Upper: 8.37
Measurand Mean 11.9
Measurand Min
Measurand Max
Measurand SD

Coding