Morris HA, Wishart JM, Horowitz M, Need AG and Nordin BEC, 1990, Ann Clin Biochem, 27, 562-8 , The reproducibility of bone-related biochemical variables in post-menopausal women


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C10

Item Details

Parameter Score
Matrix Serum
Measurand Creatinine
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; Other
Number of Subjects 60
Number of Subjects included in BV estimation 2
Ethinicity Caucasian
Age Mean / Median
Age Min 46.0
Age Max 77.0
Age SD
Number of Males
Number of Females 60
State of Well Being Healthy (excl pregnant)
Study Duration Length 35
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Year
Sampling Times Start Time: 08:00
End Time: 09:00
Number of Samples 2
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 6.3
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 49.34
Estimates of CVg 14.3
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 96.28
Analytical CV 5.0
Calculated Confidence Intervals of Analytical CV Lower: 2.23, Upper: 159.55
Measurand Mean
Measurand Min
Measurand Max
Measurand SD


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