Included in meta analysis


Harris EK, Kanofsky P, Shakarji G and Cotlove E, 1970, Clin Chem, 16, 1022-7 , Biological and analytic components of variation in long-term studies of serum constituents in normal subjects

Originally from this reference: Clin Chem, Harris EK, Kanofsky P, Shakarji G and Cotlove E, 1970

ID: 0069


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Urea
Unit mmol / L
Overall Analytical Principle Method Unknown
Number of Subjects 68
Number of Subjects included in BV estimation 68
Ethinicity Unknown
Age Mean / Median
Age Min 20.0
Age Max 59.0
Age SD
Number of Males
Number of Females
State of Well Being Healthy (excl pregnant)
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 8:30
End Time: 9:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 11.9
Calculated Confidence Intervals of CVi Lower: 11.13, Upper: 12.75
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 7.4
Calculated Confidence Intervals of Analytical CV Lower: 7.03, Upper: 7.82
Measurand Mean
Measurand Min
Measurand Max
Measurand SD


Parameter Score
Healthy Population true
Adult Population true
Weekly Samplings true
Reviewed true
Published true
Gender for Meta-Analysis Mixed
Snomed CT