EFLM Biological Varation Database : BIVAC Minimum Data Set for Immunoglobulin A (IgA) EFLM Biological Variation

Immunoglobulin A (IgA)

Reference

Fraser CG., Cummings ST., Wilkinson SP., Neville RG., Knox JDE, Ho O and MacWalter RS, 1989, Clin Chem, 35, 783-6 , Biological variability of 26 clinical chemistry analytes in elderly people

Originally from this reference: Clin Chem, Fraser CG., Cummings ST., Wilkinson SP., Neville RG., Knox JDE, Ho O and MacWalter RS, 1989

ID: 0049

Scoring

Total Score

C_8,10,13

Parameter	Score
1. Scale	A
2. Study Population	B
3. Samples	B
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_8,10,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Immunoglobulin A (IgA)
Unit	g / L
Overall Analytical Principle Method	Unknown
Number of Subjects	27
Number of Subjects included in BV estimation	27
Ethinicity	Unknown
Age Mean / Median
Age Min	70.0
Age Max	83.0
Age SD
Number of Males	14
Number of Females	13
State of Well Being	Healthy (excl pregnant)
Study Duration Length	140
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	2
Interval Units	Month
Sampling Times	Start Time: 07:00 End Time: 09:00
Number of Samples	10
Average Number of Samples Used for BV Estimation	10.0
Average Number of Replicates	2.0
Estimates of CVi	8.6
Calculated Confidence Intervals of CVi	Lower: 7.83, Upper: 9.51
Estimates of CVg	36.8
Calculated Confidence Intervals of CVg	Lower: 29.04, Upper: 50.16
Analytical CV	3.6
Calculated Confidence Intervals of Analytical CV	Lower: 3.32, Upper: 3.93
Measurand Mean	2.24
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	false
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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