Free kappa light chain level

Included in meta analysis

Reference

Reference
Ford RP, Mitchell PEG, Fraser CG., 1988, Clin Chem , 34, 1733-36 , Desirable performance characteristics and clinical utility of immunoglobulin and light-chain assays derived from data on biological variation

Scoring

Total Score

C10

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality B
10. Variance Homogeneity C
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C10
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Free kappa light chain level
Unit mg / L
Overall Analytical Principle Method Electrophoresis; Other
Number of Subjects 12
Number of Subjects included in BV estimation 12
Ethinicity Caucasian
Age Mean / Median
Age Min 23.0
Age Max 48.0
Age SD
Number of Males 6
Number of Females 6
State of Well Being Healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 0800
End Time: 0930
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 4.8
Calculated Confidence Intervals of CVi Lower: 4.22, Upper: 5.56
Estimates of CVg 15.3
Calculated Confidence Intervals of CVg Lower: 10.92, Upper: 25.34
Analytical CV 1.1
Calculated Confidence Intervals of Analytical CV Lower: 0.98, Upper: 1.26
Measurand Mean 7910.0
Measurand Min
Measurand Max
Measurand SD

Coding

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