Reference
Ford RP, Mitchell PEG, Fraser CG., 1988, Clin Chem , 34, 1733-36 , Desirable performance characteristics and clinical utility of immunoglobulin and light-chain assays derived from data on biological variation
Originally from this reference: Clin Chem , Ford RP, Mitchell PEG, Fraser CG., 1988
ID: 0042
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | B |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | C10 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Immunoglobulin M (IgM) |
| Unit | mg / L |
| Overall Analytical Principle Method | Electrophoresis; Other |
| Number of Subjects | 12 |
| Number of Subjects included in BV estimation | 12 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 23.0 |
| Age Max | 48.0 |
| Age SD | |
| Number of Males | 6 |
| Number of Females | 6 |
| State of Well Being | Healthy (excl pregnant) |
| Study Duration Length | 5 |
| Study Duration Units | Month |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Month |
| Sampling Times | Start Time:
0800
End Time: 0930 |
| Number of Samples | 10 |
| Average Number of Samples Used for BV Estimation | 10.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 5.9 |
| Calculated Confidence Intervals of CVi | Lower: 5.12, Upper: 6.90 |
| Estimates of CVg | 48.5 |
| Calculated Confidence Intervals of CVg | Lower: 34.75, Upper: 80.10 |
| Analytical CV | 2.7 |
| Calculated Confidence Intervals of Analytical CV | Lower: 2.40, Upper: 3.09 |
| Measurand Mean | 1023.0 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |