Troponin T, cardiac - high-sensitive (biweekly-monthly sampling)


Klinkenberg LJ, Van Dijk JW, Tan FES, Van Loon LJC, Van Dieijen-Visser MP and Meex SJR, 2014, J Am Col Cardiol, 63, 1788-95 , Circulating Cardiac Troponin T Exhibits a Diurnal Rhythm


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis B
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score B8,13
Comment Diabetes and obesity. Activity. Results excluded <LoD

Item Details

Parameter Score
Matrix Plasma
Measurand Troponin T, cardiac - high-sensitive (biweekly-monthly sampling)
Unit ng / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 23
Number of Subjects included in BV estimation 23
Ethinicity Caucasian
Age Mean / Median 63.0
Age Min
Age Max
Age SD 7.0
Number of Males 23
Number of Females
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 11
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 9
Average Number of Samples Used for BV Estimation 9.0
Average Number of Replicates 2.0
Estimates of CVi 12.7
Calculated Confidence Intervals of CVi Lower: 11.51, Upper: 14.16
Estimates of CVg 40.4
Calculated Confidence Intervals of CVg Lower: 31.28, Upper: 56.82
Analytical CV 1.9
Calculated Confidence Intervals of Analytical CV Lower: 1.73, Upper: 2.10
Measurand Mean 11.3
Measurand Min
Measurand Max
Measurand SD