Troponin T, cardiac - high-sensitive (biweekly-monthly sampling)


Frankenstein L, Wu AH, Hallermayer K, Wians FH Jr, Giannitsis E, Katus HA., 2011, Clin Chem, 57(7), 1068-71 , Biological variation and reference change value of high-sensitivity troponin T in healthy individuals during short and intermediate follow-up periods.


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C8,10,13
Comment Elecsys E-170. Results excluded: < LoB

Item Details

Parameter Score
Matrix Plasma
Measurand Troponin T, cardiac - high-sensitive (biweekly-monthly sampling)
Unit ng / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 20
Number of Subjects included in BV estimation 20
Ethinicity Caucasian
Age Mean / Median 32.0
Age Min 22.0
Age Max 59.0
Age SD
Number of Males 7
Number of Females 13
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 21.0
Calculated Confidence Intervals of CVi Lower: 17.83, Upper: 25.22
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 9.7
Calculated Confidence Intervals of Analytical CV Lower: 8.52, Upper: 11.26
Measurand Mean
Measurand Min 3.0
Measurand Max 16.0
Measurand SD