EFLM Biological Varation Database : BIVAC Minimum Data Set for Noradrenaline level EFLM Biological Variation

Noradrenaline level

Reference

Li XS, Li S, Wynveen P et al. , 2014, Anal Bioanal Chem, 406, 7287-97 , Development and validation of a specific and sensitive LC-MS/MS method for quantification of urinary catecholamines and application in biological variation studies

Originally from this reference: Anal Bioanal Chem, Li XS, Li S, Wynveen P et al. , 2014

ID: 0447

Scoring

Total Score

C_7,8,10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	C
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_7,8,10,13
Comment

Item Details

Parameter	Score
Matrix	Morning urine
Measurand	Noradrenaline level
Unit	ug / Unknown
Overall Analytical Principle Method	MS; MS-MS
Number of Subjects	25
Number of Subjects included in BV estimation	25
Ethinicity	Unknown
Age Mean / Median	33.0
Age Min	24.0
Age Max	58.0
Age SD
Number of Males	10
Number of Females	15
State of Well Being	Healthy (excl pregnant)
Study Duration Length	3
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	7
Interval Units	Day
Sampling Times	Start Time: 08:00 End Time: 08:00
Number of Samples	24
Average Number of Samples Used for BV Estimation	24.0
Average Number of Replicates	3.0
Estimates of CVi
Calculated Confidence Intervals of CVi	Lower: , Upper:
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV	4.4
Calculated Confidence Intervals of Analytical CV	Lower: 4.23, Upper: 4.58
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	false
Reviewed	true
Published	false
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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