Noradrenaline level


Li XS, Li S, Wynveen P et al. , 2014, Anal Bioanal Chem, 406, 7287-97 , Development and validation of a specific and sensitive LC-MS/MS method for quantification of urinary catecholamines and application in biological variation studies

Originally from this reference: Anal Bioanal Chem, Li XS, Li S, Wynveen P et al. , 2014

ID: 0447


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Morning urine
Measurand Noradrenaline level
Unit ug / Unknown
Overall Analytical Principle Method MS; MS-MS
Number of Subjects 25
Number of Subjects included in BV estimation 25
Ethinicity Unknown
Age Mean / Median 33.0
Age Min 24.0
Age Max 58.0
Age SD
Number of Males 10
Number of Females 15
State of Well Being Healthy (excl pregnant)
Study Duration Length 3
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 7
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 08:00
Number of Samples 24
Average Number of Samples Used for BV Estimation 24.0
Average Number of Replicates 3.0
Estimates of CVi
Calculated Confidence Intervals of CVi Lower: , Upper:
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 4.4
Calculated Confidence Intervals of Analytical CV Lower: 4.23, Upper: 4.58
Measurand Mean
Measurand Min
Measurand Max
Measurand SD


Parameter Score
Healthy Population true
Adult Population true
Weekly Samplings false
Reviewed true
Published false
Gender for Meta-Analysis Mixed
Snomed CT
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