Homovanillic acid (HVA)


Curtin F, Walker JP and Schulz P, 1996, J Affect Dissord, 38, 173-8 , Day-to-day intraindividual reliability and interindividual differences in monoamines excretion


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Urine
Measurand Homovanillic acid (HVA)
Unit mg / Unknown
Overall Analytical Principle Method Chromatography; HPLC
Number of Subjects 44
Number of Subjects included in BV estimation 44
Ethinicity Caucasian
Age Mean / Median 26.6
Age Min 25.0
Age Max 35.0
Age SD
Number of Males 44
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 20:00
End Time: 7:00
Number of Samples 2
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 41.0
Calculated Confidence Intervals of CVi Lower: 33.93, Upper: 51.84
Estimates of CVg 71.3
Calculated Confidence Intervals of CVg Lower: 56.21, Upper: 92.85
Analytical CV 3.0
Calculated Confidence Intervals of Analytical CV Lower: 2.03, Upper: 5.75
Measurand Mean
Measurand Min
Measurand Max
Measurand SD