Reference
Andersson AM, Carlsen E, Petersen JH and Skakkebaek NE, 2003, J Clin Endocrinol Metab, 88, 932-937 , Variation in levels of serum Inhibin B, testosterone, estradiol, luteinizing hormone, follicle-stimulating hormone and sex hormone binding globulin in monthly samples from healthy men during a 17-month period: possible effects of seasons
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | B |
| 7. Steady State | C |
| 8. Outlier Analysis | C |
| 9. Normality | A |
| 10. Variance Homogeneity | C |
| 11. ANOVA | C |
| 12. CI | A |
| 13. No of Results | C |
| 14. Concentrations | B |
| 15. Total Score | C7,8,10,11,13 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Estradiol |
| Unit | pmol / L |
| Overall Analytical Principle Method | Immunoassay; RIA |
| Number of Subjects | 27 |
| Number of Subjects included in BV estimation | 27 |
| Ethinicity | Caucasian |
| Age Mean / Median | 24.4 |
| Age Min | 20.0 |
| Age Max | 37.2 |
| Age SD | |
| Number of Males | 27 |
| Number of Females | |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 17 |
| Study Duration Units | Month |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Month |
| Sampling Times | Start Time:
8:15
End Time: 12:00 |
| Number of Samples | 16 |
| Average Number of Samples Used for BV Estimation | 16.0 |
| Average Number of Replicates | 1.0 |
| Estimates of CVi | 15.0 |
| Calculated Confidence Intervals of CVi | Lower: 13.26, Upper: 16.51 |
| Estimates of CVg | 13.0 |
| Calculated Confidence Intervals of CVg | Lower: 9.94, Upper: 18.11 |
| Analytical CV | 8.0 |
| Calculated Confidence Intervals of Analytical CV | Lower: 6.61, Upper: 10.14 |
| Measurand Mean | |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |