EFLM Biological Varation Database : BIVAC Minimum Data Set for Cortisol EFLM Biological Variation

Cortisol

Reference

Casals G, Foj L, Martínez de Osaba MJ, 2011, Clin Biochem, 44, 665-8 , Day-to-day variation of late-night salivary cortisol in healthy voluntaries

Originally from this reference: Clin Biochem, Casals G, Foj L, Martínez de Osaba MJ, 2011

ID: 0432

Scoring

Total Score

C_4,7,11,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	C
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	C
8. Outlier Analysis	B
9. Normality	B
10. Variance Homogeneity	A
11. ANOVA	C
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_4,7,11,13
Comment

Item Details

Parameter	Score
Matrix	Salivary
Measurand	Cortisol
Unit	nmol / L
Overall Analytical Principle Method	Spectrophotometry; UV/VISIBLE
Number of Subjects	20
Number of Subjects included in BV estimation
Ethinicity	Unknown
Age Mean / Median
Age Min	25.0
Age Max	65.0
Age SD
Number of Males	7
Number of Females	13
State of Well Being	Healthy (excl pregnant)
Study Duration Length	2
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Day
Sampling Times	Start Time: End Time:
Number of Samples	2
Average Number of Samples Used for BV Estimation
Average Number of Replicates	1.0
Estimates of CVi	32.1
Calculated Confidence Intervals of CVi	Lower: 0.00, Upper: 48.65
Estimates of CVg	38.1
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper: 60.80
Analytical CV	14.6
Calculated Confidence Intervals of Analytical CV	Lower: 8.75, Upper: 41.95
Measurand Mean	135.0
Measurand Min	0.36
Measurand Max	3.42
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	false
Reviewed	false
Published	false
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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