Casals G, Foj L, Martínez de Osaba MJ, 2011, Clin Biochem, 44, 665-8 , Day-to-day variation of late-night salivary cortisol in healthy voluntaries


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand C
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C4,7,11,13

Item Details

Parameter Score
Matrix Salivary
Measurand Cortisol
Unit nmol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 20
Number of Subjects included in BV estimation
Ethinicity Unknown
Age Mean / Median
Age Min 25.0
Age Max 65.0
Age SD
Number of Males 7
Number of Females 13
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time:
End Time:
Number of Samples 2
Average Number of Samples Used for BV Estimation
Average Number of Replicates 1.0
Estimates of CVi 32.1
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 48.65
Estimates of CVg 38.1
Calculated Confidence Intervals of CVg Lower: 19.67, Upper: 60.80
Analytical CV 14.6
Calculated Confidence Intervals of Analytical CV Lower: 8.75, Upper: 41.95
Measurand Mean 135.0
Measurand Min 0.36
Measurand Max 3.42
Measurand SD