Casals G, Foj L, Martínez de Osaba MJ, 2011, Clin Biochem, 44, 665-8 , Day-to-day variation of late-night salivary cortisol in healthy voluntaries


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand C
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C4,7,11,13

Item Details

Parameter Score
Matrix Salivary
Measurand Cortisol
Unit nmol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 7
Number of Subjects included in BV estimation
Ethinicity Unknown
Age Mean / Median
Age Min 26.0
Age Max 65.0
Age SD
Number of Males 3
Number of Females 4
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time: 23:30
End Time: 00:00
Number of Samples 8
Average Number of Samples Used for BV Estimation 8.0
Average Number of Replicates 1.0
Estimates of CVi 30.4
Calculated Confidence Intervals of CVi Lower: 19.31, Upper: 38.66
Estimates of CVg 35.3
Calculated Confidence Intervals of CVg Lower: 21.62, Upper: 74.56
Analytical CV 10.4
Calculated Confidence Intervals of Analytical CV Lower: 6.49, Upper: 25.51
Measurand Mean 1.27
Measurand Min 0.69
Measurand Max 2.01
Measurand SD