Cortisol

Reference

Reference
Chiu SK, Collier CP, Clark AF and Wynn-Edwards KE, 2003, Clin Biochem, 36, 211-14 , Salivary cortisol on ROCHE Elecsys immunoassay system: pilot biological variation studies

Scoring

Total Score

C7,11

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity A
11. ANOVA C
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C7,11
Comment

Item Details

Parameter Score
Matrix Salivary
Measurand Cortisol
Unit nmol / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 28
Number of Subjects included in BV estimation
Ethinicity Unknown
Age Mean / Median 23.0
Age Min 10.0
Age Max 65.0
Age SD
Number of Males 12
Number of Females 16
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 2
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 6.3
Calculated Confidence Intervals of CVi Lower: 3.55, Upper: 7.83
Estimates of CVg 20.5
Calculated Confidence Intervals of CVg Lower: 16.11, Upper: 27.92
Analytical CV 3.8
Calculated Confidence Intervals of Analytical CV Lower: 2.69, Upper: 6.45
Measurand Mean 20.4
Measurand Min
Measurand Max
Measurand SD

Coding