EFLM Biological Varation Database : BIVAC Minimum Data Set for Basophils EFLM Biological Variation

Basophils

Reference

Thyagarajan B, Howard AG, Durazo-Arvizu R, Eckfeldt JH, Gellman MD, Kim RS, Liu K, Mendez AJ, Penedo FJ, Talavera GA, Youngblood ME, Zhao L and Sotres-Alvarez D, 2016, Clin Chim Acta, 463, 129-137 , Analytical and biological variability in biomarker measurement in the Hispanic Community Health Study/Study of Latinos

Scoring

Total Score

C_7,8,10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	C
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_7,8,10,13
Comment

Item Details

Parameter	Score
Matrix	Whole Blood EDTA
Measurand	Basophils
Unit	10(9) / L
Overall Analytical Principle Method	Flow cytometry - Laser
Number of Subjects	24
Number of Subjects included in BV estimation	24
Ethinicity	Unknown
Age Mean / Median
Age Min	18.0
Age Max	44.0
Age SD
Number of Males
Number of Females
State of Well Being	Healthy (excl pregnant)
Study Duration Length	1
Study Duration Units	Month
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Month
Sampling Times	Start Time: End Time:
Number of Samples	2
Average Number of Samples Used for BV Estimation	2.0
Average Number of Replicates	1.0
Estimates of CVi	119.2
Calculated Confidence Intervals of CVi	Lower: 93.09, Upper: 165.84
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV	2.1
Calculated Confidence Intervals of Analytical CV	Lower: 1.26, Upper: 6.03
Measurand Mean	0.0
Measurand Min
Measurand Max
Measurand SD

Coding

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