Reference
Thyagarajan B, Howard AG, Durazo-Arvizu R, Eckfeldt JH, Gellman MD, Kim RS, Liu K, Mendez AJ, Penedo FJ, Talavera GA, Youngblood ME, Zhao L and Sotres-Alvarez D, 2016, Clin Chim Acta, 463, 129-137 , Analytical and biological variability in biomarker measurement in the Hispanic Community Health Study/Study of Latinos
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | B |
| 7. Steady State | C |
| 8. Outlier Analysis | C |
| 9. Normality | B |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | C |
| 14. Concentrations | A |
| 15. Total Score | C7,8,10,13 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Whole Blood EDTA |
| Measurand | Basophils |
| Unit | 10(9) / L |
| Overall Analytical Principle Method | Flow cytometry - Laser |
| Number of Subjects | 24 |
| Number of Subjects included in BV estimation | 24 |
| Ethinicity | Unknown |
| Age Mean / Median | |
| Age Min | 18.0 |
| Age Max | 44.0 |
| Age SD | |
| Number of Males | |
| Number of Females | |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 1 |
| Study Duration Units | Month |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Month |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 2 |
| Average Number of Samples Used for BV Estimation | 2.0 |
| Average Number of Replicates | 1.0 |
| Estimates of CVi | 119.2 |
| Calculated Confidence Intervals of CVi | Lower: 93.09, Upper: 165.84 |
| Estimates of CVg | |
| Calculated Confidence Intervals of CVg | Lower: 0.00, Upper: |
| Analytical CV | 2.1 |
| Calculated Confidence Intervals of Analytical CV | Lower: 1.26, Upper: 6.03 |
| Measurand Mean | 0.0 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |