Reference
Alvarez L, Ricós C, Peris P, Guañabens N, Monegal A,Pons F and Ballesta AM, 2000, Bone, 26, 571-6 , Components of biological variation of biochemical markers of bone tumor in Paget’s bone disease
Originally from this reference: Bone, Alvarez L, Ricós C, Peris P, Guañabens N, Monegal A,Pons F and Ballesta AM, 2000
ID: 0171
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | C |
| 9. Normality | A |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | C |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | C8,10,12 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Procollagen type I N-terminal propeptide (PINP) |
| Unit | ng / mL |
| Overall Analytical Principle Method | Immunoassay; RIA |
| Number of Subjects | 15 |
| Number of Subjects included in BV estimation | 15 |
| Ethinicity | Unknown |
| Age Mean / Median | 40.0 |
| Age Min | 28.0 |
| Age Max | 49.0 |
| Age SD | 6.2 |
| Number of Males | |
| Number of Females | 15 |
| State of Well Being | Non-healthy (excl pregnant) |
| Study Duration Length | 1 |
| Study Duration Units | Year |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 3 |
| Interval Units | Month |
| Sampling Times | Start Time:
8:00
End Time: 10:00 |
| Number of Samples | 4 |
| Average Number of Samples Used for BV Estimation | 4.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 10.0 |
| Calculated Confidence Intervals of CVi | Lower: 7.63, Upper: 13.23 |
| Estimates of CVg | 41.6 |
| Calculated Confidence Intervals of CVg | Lower: 30.49, Upper: 64.72 |
| Analytical CV | 7.4 |
| Calculated Confidence Intervals of Analytical CV | Lower: 6.28, Upper: 9.01 |
| Measurand Mean | 176.5 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |