Pyridinoline level


Beck Jensen et al. , 1997, Scand J Clin Lab Invest, 57, 351-60 , A single measurement of biochemical markers of bone turnover has limited utility in the individual person.


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical B
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Random Urine
Measurand Pyridinoline level
Unit nmol / mmol creatinine
Overall Analytical Principle Method Chromatography; HPLC
Number of Subjects 30
Number of Subjects included in BV estimation 30
Ethinicity Unknown
Age Mean / Median
Age Min 24.0
Age Max 62.0
Age SD
Number of Males
Number of Females 30
State of Well Being
Healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 8.5
Calculated Confidence Intervals of CVi Lower: 5.55, Upper: 11.17
Estimates of CVg 20.5
Calculated Confidence Intervals of CVg Lower: 16.01, Upper: 27.86
Analytical CV 13.28
Calculated Confidence Intervals of Analytical CV Lower: 11.93, Upper: 14.97
Measurand Mean
Measurand Min
Measurand Max
Measurand SD