C-terminal cross-linked telopeptide of type I collagen (CTX)


Garnero P, Mullerman D, Munoz F et al, 2003, J Bone Min Res, 18(10), 1789-94 , Long-Term Variability of Markers of Bone Turnover in Postmenopausal Women and Implications for Their Clinical Use: The OFELY Study


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis C
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C6,7,8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand C-terminal cross-linked telopeptide of type I collagen (CTX)
Unit pg / mL
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 268
Number of Subjects included in BV estimation 268
Ethinicity Unknown
Age Mean / Median 63.0
Age Min 50.0
Age Max 88.0
Age SD 8.0
Number of Males
Number of Females 268
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Year
Sampling Times Start Time: 8:00
End Time: 9:30
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates
Estimates of CVi 18.0
Calculated Confidence Intervals of CVi Lower: , Upper:
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV
Calculated Confidence Intervals of Analytical CV Lower: , Upper:
Measurand Mean 14.3
Measurand Min
Measurand Max
Measurand SD 4.7