C-terminal cross-linked telopeptide of type I collagen (CTX)


Stevenson HP, Leslie H, Sheridan B, 1997, Ann Clin Biochem, 34, 317-8 , Intra-individual variation in serum type I procollagen carboxy-terminal propeptide and type I collagen carboxy-terminal cross-linked telopeptide concentrations


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples C
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C3,7,8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand C-terminal cross-linked telopeptide of type I collagen (CTX)
Unit ug / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 10
Number of Subjects included in BV estimation 10
Ethinicity Unknown
Age Mean / Median
Age Min 27.0
Age Max 52.0
Age SD
Number of Males 6
Number of Females 4
State of Well Being
Healthy (excl pregnant)
Study Duration Length 3
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Month
Sampling Times Start Time: 8:30
End Time: 9:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 3.0
Estimates of CVi 6.9
Calculated Confidence Intervals of CVi Lower: 5.88, Upper: 8.23
Estimates of CVg 28.8
Calculated Confidence Intervals of CVg Lower: 20.05, Upper: 50.65
Analytical CV 4.5
Calculated Confidence Intervals of Analytical CV Lower: 4.10, Upper: 4.99
Measurand Mean
Measurand Min
Measurand Max
Measurand SD