EFLM Biological Varation Database : BIVAC Minimum Data Set for Alkaline phosphatase (ALP) bone isoenzyme EFLM Biological Variation

Alkaline phosphatase (ALP) bone isoenzyme

Reference

Blomshon A, Hannon RA, Al-Dehaimi AW and Eastell R, 1995, XXIV European Symposium on Calcified Tissues, , , Short-term intraindividual variability of markers of bone turnover in healthy adults

Scoring

Total Score

C_{5,7,8,10,12,13}

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	C
6. Replicate Analysis	B
7. Steady State	C
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	C
13. No of Results	C
14. Concentrations	B
15. Total Score	C_{5,7,8,10,12,13}
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Alkaline phosphatase (ALP) bone isoenzyme
Unit	Unknown / Unknown
Overall Analytical Principle Method	Electrophoresis; Other
Number of Subjects	10
Number of Subjects included in BV estimation	5
Ethinicity	Unknown
Age Mean / Median
Age Min	23.0
Age Max	44.0
Age SD
Number of Males	5
Number of Females	5
State of Well Being	Healthy (excl pregnant)
Study Duration Length	5
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Day
Sampling Times	Start Time: 09:30 End Time:
Number of Samples	5
Average Number of Samples Used for BV Estimation	5.0
Average Number of Replicates	2.0
Estimates of CVi	3.5
Calculated Confidence Intervals of CVi	Lower: 1.71, Upper: 5.68
Estimates of CVg	35.9
Calculated Confidence Intervals of CVg	Lower: 22.36, Upper: 88.15
Analytical CV	3.5
Calculated Confidence Intervals of Analytical CV	Lower: 2.74, Upper: 4.83
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding

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