Alkaline phosphatase (ALP) bone isoenzyme

Reference

Reference
Blomshon A, Hannon RA, Al-Dehaimi AW and Eastell R, 1995, XXIV European Symposium on Calcified Tissues, , , Short-term intraindividual variability of markers of bone turnover in healthy adults

Scoring

Total Score

C5,7,8,10,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA A
12. CI C
13. No of Results C
14. Concentrations B
15. Total Score C5,7,8,10,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Alkaline phosphatase (ALP) bone isoenzyme
Unit Unknown / Unknown
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 10
Number of Subjects included in BV estimation 5
Ethinicity Unknown
Age Mean / Median
Age Min 23.0
Age Max 44.0
Age SD
Number of Males 5
Number of Females 5
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 5
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 09:30
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 4.9
Calculated Confidence Intervals of CVi Lower: 3.67, Upper: 7.17
Estimates of CVg 41.4
Calculated Confidence Intervals of CVg Lower: 25.78, Upper: 101.66
Analytical CV 1.6
Calculated Confidence Intervals of Analytical CV Lower: 1.25, Upper: 2.21
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding