Protein (total)

Included in meta analysis


Williams GZ, Widdowson GM and Penton J, 1978, Clin Chem, 24, 313-20 , Individual Character of Variation in Time-Series Studies of Healthy People II. Differences in Values for Clinical Chemical Analytes in Serum among Demographic Groups by Age and Sex


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Protein (total)
Unit g / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 1105
Number of Subjects included in BV estimation 1105
Ethinicity Caucasian
Age Mean / Median
Age Min 18.0
Age Max 70.0
Age SD
Number of Males 628
Number of Females 477
State of Well Being
Healthy (excl pregnant)
Study Duration Length 12
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 9
Average Number of Samples Used for BV Estimation 8.5
Average Number of Replicates 1.0
Estimates of CVi 4.7
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 11.23
Estimates of CVg 3.3
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 5.21
Analytical CV 1.2
Calculated Confidence Intervals of Analytical CV Lower: 1.15, Upper: 1.26
Measurand Mean 70.0
Measurand Min
Measurand Max
Measurand SD