Reference
Hannon R, Blumsohn A, Naylor K, Eastell R., 1998, J Bone Mineral Res, 13, 1124-33 , Response of biochemical markers of bone turnover to hormone replacement therapy: impact of biological variability
Originally from this reference: J Bone Mineral Res, Hannon R, Blumsohn A, Naylor K, Eastell R., 1998
ID: 0067
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | C10 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Osteocalcin level |
| Unit | ug / L |
| Overall Analytical Principle Method | Immunoassay; RIA |
| Number of Subjects | 11 |
| Number of Subjects included in BV estimation | 11 |
| Ethinicity | Unknown |
| Age Mean / Median | |
| Age Min | 49.0 |
| Age Max | 56.0 |
| Age SD | |
| Number of Males | |
| Number of Females | 11 |
| State of Well Being | Non-healthy (excl pregnant) |
| Study Duration Length | 24 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
9:00
End Time: 10:00 |
| Number of Samples | 24 |
| Average Number of Samples Used for BV Estimation | 24.0 |
| Average Number of Replicates | 1.0 |
| Estimates of CVi | 7.2 |
| Calculated Confidence Intervals of CVi | Lower: 6.03, Upper: 8.13 |
| Estimates of CVg | |
| Calculated Confidence Intervals of CVg | Lower: 0.00, Upper: |
| Analytical CV | 3.9 |
| Calculated Confidence Intervals of Analytical CV | Lower: 3.07, Upper: 5.34 |
| Measurand Mean | 8.44 |
| Measurand Min | 5.7 |
| Measurand Max | 13.0 |
| Measurand SD |
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European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy
biologicalvariationdatabase@eflm.eu
European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy
biologicalvariationdatabase@eflm.eu