EFLM Biological Varation Database : BIVAC Minimum Data Set for Mean corpuscular volume (MCV) EFLM Biological Variation

Mean corpuscular volume (MCV)

Reference

Buoro S, Carobene A, Seghezzi M, Manenti B, Dominoni P, Pacioni A, Ceriotti F, Ottomano C and Lippi G, 2018, Clin Chem Lab Med, , , Short- and medium-term biological variation estimates of red blood cell and reticulocyte parameters in healthy subjects

Originally from this reference: Clin Chem Lab Med, Buoro S, Carobene A, Seghezzi M, Manenti B, Dominoni P, Pacioni A, Ceriotti F, Ottomano C and Lippi G, 2018

ID: 0334

Scoring

Total Score

A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	A
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	A
12. CI	A
13. No of Results	A
14. Concentrations	A
15. Total Score	A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}
Comment

Item Details

Parameter	Score
Matrix	Whole Blood EDTA
Measurand	Mean corpuscular volume (MCV)
Unit	fL / _
Overall Analytical Principle Method	Flow cytometry - Laser
Number of Subjects	12
Number of Subjects included in BV estimation	12
Ethinicity	Caucasian
Age Mean / Median
Age Min	18.0
Age Max	64.0
Age SD
Number of Males	12
Number of Females	0
State of Well Being	Healthy (excl pregnant)
Study Duration Length	5
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Day
Sampling Times	Start Time: 08.00 End Time: 08.30
Number of Samples	5
Average Number of Samples Used for BV Estimation	5.0
Average Number of Replicates	2.0
Estimates of CVi	0.6
Calculated Confidence Intervals of CVi	Lower: 0.50, Upper: 0.75
Estimates of CVg	3.5
Calculated Confidence Intervals of CVg	Lower: 2.50, Upper: 5.79
Analytical CV	0.16
Calculated Confidence Intervals of Analytical CV	Lower: 0.14, Upper: 0.19
Measurand Mean	85.8
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	false
Reviewed	true
Published	true
Gender for Meta-Analysis	Males
Snomed CT
NPU
LOINC
Comment

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