Lymphocytes

Reference

Reference
Buoro S, Carobene A, Seghezzi M, Manenti B, Pacioni A, Ceriotti F, Ottomano C and Lippi G, 2017, Clin Chim Acta, 473, 147-56 , Short and medium-term biological variation estimates of leukocytes extended to differential count and morphology-structural paràmetres (cell population data) in blood samples obtained from healthy people

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Lymphocytes
Unit 10(9) / L
Overall Analytical Principle Method Flow cytometry - Laser
Number of Subjects 22
Number of Subjects included in BV estimation 21
Ethinicity Caucasian
Age Mean / Median
Age Min 18.0
Age Max 64.0
Age SD
Number of Males 12
Number of Females 10
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 5
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 08.00
End Time: 08.30
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 8.3
Calculated Confidence Intervals of CVi Lower: 7.15, Upper: 9.85
Estimates of CVg 26.5
Calculated Confidence Intervals of CVg Lower: 20.24, Upper: 38.07
Analytical CV 2.73
Calculated Confidence Intervals of Analytical CV Lower: 2.41, Upper: 3.16
Measurand Mean 2.11
Measurand Min
Measurand Max
Measurand SD

Coding