Included in meta analysis


Dot D, Miró J, Fuentes-Arderiu X., 1992, Scand J Clin Lab Invest, 952, 607-11 , Biological variation of the leukocyte differential count quantities


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Lymphocytes
Unit 10(9) / L
Overall Analytical Principle Method Flow cytometry - Laser
Number of Subjects 39
Number of Subjects included in BV estimation 39
Ethinicity Unknown
Age Mean / Median
Age Min 22.0
Age Max 49.0
Age SD
Number of Males 20
Number of Females 19
State of Well Being
Healthy (excl pregnant)
Study Duration Length 12
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 08.00
End Time: 10
Number of Samples 12
Average Number of Samples Used for BV Estimation 12.0
Average Number of Replicates 1.0
Estimates of CVi 12.3
Calculated Confidence Intervals of CVi Lower: 10.83, Upper: 13.54
Estimates of CVg 21.3
Calculated Confidence Intervals of CVg Lower: 17.29, Upper: 27.54
Analytical CV 6.9
Calculated Confidence Intervals of Analytical CV Lower: 5.73, Upper: 8.67
Measurand Mean 2.0
Measurand Min
Measurand Max
Measurand SD