Dot D, Miró J, Fuentes-Arderiu X., 1992, Scand J Clin Lab Invest, 952, 607-11 , Biological variation of the leukocyte differential count quantities


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Leukocytes
Unit 10(9) / L
Overall Analytical Principle Method Flow cytometry - Laser
Number of Subjects 19
Number of Subjects included in BV estimation 19
Ethinicity Unknown
Age Mean / Median
Age Min 22.0
Age Max 49.0
Age SD
Number of Males 0
Number of Females 19
State of Well Being
Healthy (excl pregnant)
Study Duration Length 12
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 08.00
End Time: 10
Number of Samples 12
Average Number of Samples Used for BV Estimation 12.0
Average Number of Replicates 1.0
Estimates of CVi 15.4
Calculated Confidence Intervals of CVi Lower: 14.00, Upper: 17.08
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 2.8
Calculated Confidence Intervals of Analytical CV Lower: 2.17, Upper: 3.96
Measurand Mean 6.4
Measurand Min
Measurand Max
Measurand SD