Statland BE, Winkel P, Harris SC, Burdsall MJ, Saunders AM, 1977, Am J Clin Pathol, 69, 48-54 , Evaluation of biological sources of variation of leukocyte counts and other hematologic quantities using very precise automated analyzers


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand B
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Leukocytes
Unit _ / _
Overall Analytical Principle Method Flow cytometry - Not specified
Number of Subjects 20
Number of Subjects included in BV estimation 20
Ethinicity Unknown
Age Mean / Median 35.5
Age Min 24.0
Age Max 46.0
Age SD
Number of Males 10
Number of Females 10
State of Well Being
Healthy (excl pregnant)
Study Duration Length 29
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 7
Interval Units Day
Sampling Times Start Time: 08.00
End Time:
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 1.0
Estimates of CVi 15.7
Calculated Confidence Intervals of CVi Lower: 14.19, Upper: 17.55
Estimates of CVg 32.7
Calculated Confidence Intervals of CVg Lower: 0.00, Upper: 47.51
Analytical CV 2.5
Calculated Confidence Intervals of Analytical CV Lower: 1.91, Upper: 3.61
Measurand Mean 6540.0
Measurand Min
Measurand Max
Measurand SD