Lymphocytes

Reference

Reference
Hilderink JM, Kilinkenberg LJJ, Aakre KM, de Wit NCJ, Henskens YMC, van der Linden N et al, 2017, Clin Chem Lab Med, 55, 1013-24 , Within-day biological variation and hour-to-hour reference change values for hematological parameters

Originally from this reference: Clin Chem Lab Med, Hilderink JM, Kilinkenberg LJJ, Aakre KM, de Wit NCJ, Henskens YMC, van der Linden N et al, 2017


ID: 0304

Scoring

Total Score

C7

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C7
Comment

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Lymphocytes
Unit 10(9) / L
Overall Analytical Principle Method Flow cytometry - Laser
Number of Subjects 24
Number of Subjects included in BV estimation 18
Ethinicity Unknown
Age Mean / Median 72.0
Age Min 58.0
Age Max 82.0
Age SD
Number of Males 19
Number of Females 5
State of Well Being Healthy (excl pregnant)
Study Duration Length 25
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 26
Average Number of Samples Used for BV Estimation 26.0
Average Number of Replicates 2.0
Estimates of CVi 15.0
Calculated Confidence Intervals of CVi Lower: 14.07, Upper: 16.07
Estimates of CVg 26.0
Calculated Confidence Intervals of CVg Lower: 19.55, Upper: 38.58
Analytical CV 2.7
Calculated Confidence Intervals of Analytical CV Lower: 2.54, Upper: 2.88
Measurand Mean 1.9
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter Score
Healthy Population false
Adult Population true
Weekly Samplings false
Reviewed true
Published true
Gender for Meta-Analysis Males
Snomed CT
NPU
LOINC
Comment Within day variation
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