Leukocytes

Reference

Reference
Hilderink JM, Kilinkenberg LJJ, Aakre KM, de Wit NCJ, Henskens YMC, van der Linden N et al, 2017, Clin Chem Lab Med, 55, 1013-24 , Within-day biological variation and hour-to-hour reference change values for hematological parameters

Scoring

Total Score

C7

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C7
Comment

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Leukocytes
Unit 10(9) / L
Overall Analytical Principle Method Flow cytometry - Laser
Number of Subjects 24
Number of Subjects included in BV estimation 17
Ethinicity Unknown
Age Mean / Median 72.0
Age Min 58.0
Age Max 82.0
Age SD
Number of Males 19
Number of Females 5
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 25
Study Duration Units Hour
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 26
Average Number of Samples Used for BV Estimation 26.0
Average Number of Replicates 2.0
Estimates of CVi 7.0
Calculated Confidence Intervals of CVi Lower: 6.55, Upper: 7.51
Estimates of CVg 13.7
Calculated Confidence Intervals of CVg Lower: 10.24, Upper: 20.60
Analytical CV 1.4
Calculated Confidence Intervals of Analytical CV Lower: 1.31, Upper: 1.50
Measurand Mean 6.6
Measurand Min
Measurand Max
Measurand SD

Coding