Protein (total)


Pineda-Tenor D , Laserna-Mendieta EJ, Timon-Zapata J, Rodelgo-Jimenez L, Ramos-Corral R, Recio-Montealegre A and Gomez-Serranillos Reus M, 2013, Clin Chem Lab Med, 51, 851-62 , Biological variation and reference change value of common clinical chemistry and haematologic laboratory analytes in the eldery population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,13

Item Details

Parameter Score
Matrix Serum
Measurand Protein (total)
Unit g / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 64
Number of Subjects included in BV estimation 52
Ethinicity Unknown
Age Mean / Median 80.0
Age Min
Age Max
Age SD
Number of Males 0
Number of Females 64
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 8
End Time: 10
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 5.1
Calculated Confidence Intervals of CVi Lower: 4.55, Upper: 5.77
Estimates of CVg 5.3
Calculated Confidence Intervals of CVg Lower: 4.19, Upper: 6.83
Analytical CV 1.2
Calculated Confidence Intervals of Analytical CV Lower: 0.92, Upper: 1.73
Measurand Mean 60.33
Measurand Min
Measurand Max
Measurand SD