Howey JEA, Browning MCk, Fraser CG., 1987, Clin Chem, 33, 269-72 , Assay of serum fructosamine that minimizes standardization and matrix problems: use to asses components of biological variation


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C10,12,13

Item Details

Parameter Score
Matrix Serum
Measurand Fructosamine
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 16
Number of Subjects included in BV estimation 16
Ethinicity Unknown
Age Mean / Median
Age Min 23.0
Age Max 46.0
Age SD
Number of Males 7
Number of Females 9
State of Well Being
Healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Week
Sampling Times Start Time: 8:30
End Time: 9:30
Number of Samples 16
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 5.3
Calculated Confidence Intervals of CVi Lower: 4.11, Upper: 6.77
Estimates of CVg 9.3
Calculated Confidence Intervals of CVg Lower: 6.66, Upper: 14.50
Analytical CV 4.5
Calculated Confidence Intervals of Analytical CV Lower: 3.90, Upper: 5.32
Measurand Mean
Measurand Min
Measurand Max
Measurand SD