Reference
Thyagarajan B, Howard AG, Durazo-Arvizu R, Eckfeldt JH, Gellman MD, Kim RS, Liu K, Mendez AJ, Penedo FJ, Talavera GA, Youngblood ME, Zhao L and Sotres-Alvarez D, 2016, Clin Chim Acta, 463, 129-137 , Analytical and biological variability in biomarker measurement in the Hispanic Community Health Study/Study of Latinos
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | B |
| 7. Steady State | B |
| 8. Outlier Analysis | B |
| 9. Normality | B |
| 10. Variance Homogeneity | C |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | B |
| 14. Concentrations | A |
| 15. Total Score | C10 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Insulin |
| Unit | mIU / L |
| Overall Analytical Principle Method | Unknown |
| Number of Subjects | 16 |
| Number of Subjects included in BV estimation | 16 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 18.0 |
| Age Max | 74.0 |
| Age SD | |
| Number of Males | 16 |
| Number of Females | |
| State of Well Being |
Non-healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 1 |
| Study Duration Units | Month |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 2 |
| Interval Units | Month |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 2 |
| Average Number of Samples Used for BV Estimation | 2.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 31.8 |
| Calculated Confidence Intervals of CVi | Lower: 23.39, Upper: 48.80 |
| Estimates of CVg | 100.76 |
| Calculated Confidence Intervals of CVg | Lower: 73.35, Upper: 155.54 |
| Analytical CV | 7.8 |
| Calculated Confidence Intervals of Analytical CV | Lower: 6.27, Upper: 10.32 |
| Measurand Mean | |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |