EFLM Biological Varation Database : BIVAC Minimum Data Set for Haematocrit (Hct) EFLM Biological Variation

Haematocrit (Hct)

Reference

Fraser CG, Wilkinson SP, Neville RG, Knox JDE, Kin g JF, MacWalter RS, 1989, Am J Clin Pathol, 92, 465-70 , Biologic variation of common hematologic laboratory quantities in the elderly

Originally from this reference: Am J Clin Pathol, Fraser CG, Wilkinson SP, Neville RG, Knox JDE, Kin g JF, MacWalter RS, 1989

ID: 0048

Scoring

Total Score

C_7,10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	C
8. Outlier Analysis	A
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_7,10,13
Comment

Item Details

Parameter	Score
Matrix	Whole Blood EDTA
Measurand	Haematocrit (Hct)
Unit	_ / _
Overall Analytical Principle Method	Flow cytometry - Laser
Number of Subjects	12
Number of Subjects included in BV estimation	12
Ethinicity	Unknown
Age Mean / Median	75.5
Age Min	70.0
Age Max	83.0
Age SD
Number of Males	0
Number of Females	12
State of Well Being	Healthy (excl pregnant)
Study Duration Length	140
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	14
Interval Units	Day
Sampling Times	Start Time: 07.00 End Time: 09.00
Number of Samples	10
Average Number of Samples Used for BV Estimation	9.9
Average Number of Replicates	2.0
Estimates of CVi	2.4
Calculated Confidence Intervals of CVi	Lower: 1.96, Upper: 2.91
Estimates of CVg	5.5
Calculated Confidence Intervals of CVg	Lower: 3.89, Upper: 9.15
Analytical CV	2.1
Calculated Confidence Intervals of Analytical CV	Lower: 1.85, Upper: 2.42
Measurand Mean	0.42
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Males
Snomed CT
NPU
LOINC
Comment	Elderly subjects

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