EFLM Biological Varation Database : BIVAC Minimum Data Set for Cholesterol EFLM Biological Variation

Cholesterol

Reference

Aarsand AK, Diaz-Garzón J, Fernández-Calle P, et al, 2018, Clin Chem, 64(9), 1380-93 , The EuBIVAS: within- and between-subject biological variation data for electrolytes, lipids, urea, uric acid, total protein, total bilirubin, direct bilirubin and glucose

Scoring

Total Score

A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	A
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	A
12. CI	A
13. No of Results	A
14. Concentrations	A
15. Total Score	A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Cholesterol
Unit	mg / dL
Overall Analytical Principle Method	Spectrophotometry; Enzymatic
Number of Subjects	10
Number of Subjects included in BV estimation	9
Ethinicity	Caucasian
Age Mean / Median	60.0
Age Min	55.0
Age Max	69.0
Age SD
Number of Males
Number of Females	10
State of Well Being	Healthy (excl pregnant)
Study Duration Length	10
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Week
Sampling Times	Start Time: 08:00 End Time: 10:00
Number of Samples	10
Average Number of Samples Used for BV Estimation	9.56
Average Number of Replicates	2.0
Estimates of CVi	4.09
Calculated Confidence Intervals of CVi	Lower: 3.52, Upper: 4.88
Estimates of CVg	14.6
Calculated Confidence Intervals of CVg	Lower: 9.99, Upper: 26.73
Analytical CV	0.98
Calculated Confidence Intervals of Analytical CV	Lower: 0.85, Upper: 1.16
Measurand Mean	232.0
Measurand Min	225.0
Measurand Max	235.8
Measurand SD

Coding

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