EFLM Biological Varation Database : BIVAC Minimum Data Set for LDL Cholesterol EFLM Biological Variation

LDL Cholesterol

Reference

Aarsand AK, Diaz-Garzón J, Fernández-Calle P, et al, 2018, Clin Chem, 64(9), 1380-93 , The EuBIVAS: within- and between-subject biological variation data for electrolytes, lipids, urea, uric acid, total protein, total bilirubin, direct bilirubin and glucose

Scoring

Total Score

A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	A
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	A
12. CI	A
13. No of Results	A
14. Concentrations	A
15. Total Score	A_{1,2,3,4,5,6,7,8,9,10,11,12,13,14}
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	LDL Cholesterol
Unit	mg / dL
Overall Analytical Principle Method	Calculated
Number of Subjects	38
Number of Subjects included in BV estimation	38
Ethinicity	Caucasian
Age Mean / Median	35.0
Age Min	22.0
Age Max	59.0
Age SD
Number of Males	38
Number of Females
State of Well Being	Healthy (excl pregnant)
Study Duration Length	10
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Week
Sampling Times	Start Time: 08:00 End Time: 10:00
Number of Samples	10
Average Number of Samples Used for BV Estimation	9.25
Average Number of Replicates	1.93
Estimates of CVi	8.55
Calculated Confidence Intervals of CVi	Lower: 7.91, Upper: 9.29
Estimates of CVg	27.0
Calculated Confidence Intervals of CVg	Lower: 22.00, Upper: 34.87
Analytical CV	1.77
Calculated Confidence Intervals of Analytical CV	Lower: 1.64, Upper: 1.92
Measurand Mean	114.8
Measurand Min	112.0
Measurand Max	118.6
Measurand SD

Coding

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