EFLM Biological Varation Database : BIVAC Minimum Data Set for Apolipoprotein A1 level EFLM Biological Variation

Apolipoprotein A1 level

Reference

Lacher DA, Hughes JP and Carroll MD, 2005, Clin Chem, 51, 450-2 , Estimate of biological variation of laboratory analytes based on the third National Health and Nutrition Examination Survey

Scoring

Total Score

C_5,7,10,13

Parameter	Score
1. Scale	A
2. Study Population	B
3. Samples	B
4. Measurand	A
5. Pre-Analytical	C
6. Replicate Analysis	B
7. Steady State	C
8. Outlier Analysis	B
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_5,7,10,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Apolipoprotein A1 level
Unit	g / L
Overall Analytical Principle Method	Enzymatic analysis - Not specified
Number of Subjects	1060
Number of Subjects included in BV estimation	1060
Ethinicity	Caucasian
Age Mean / Median	40.0
Age Min
Age Max
Age SD
Number of Males
Number of Females
State of Well Being	Healthy (excl pregnant)
Study Duration Length	84
Study Duration Units	Month
Sampling Intervals, e.g. X sample(s) per Interval Unit	2
Interval Units	Month
Sampling Times	Start Time: End Time:
Number of Samples	2
Average Number of Samples Used for BV Estimation	2.0
Average Number of Replicates	1.0
Estimates of CVi	7.0
Calculated Confidence Intervals of CVi	Lower: 6.46, Upper: 7.50
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV	4.8
Calculated Confidence Intervals of Analytical CV	Lower: 4.38, Upper: 5.30
Measurand Mean	1.44
Measurand Min
Measurand Max
Measurand SD

Coding

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