LDL Cholesterol


Rivera-Coll A, Fuentes-Arderiu X and Díez-Noguera A, 1994, Clin Chem, 40, 1549-53 , Circadian rhythmic variations in serum concentrations of clinically important lipids


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand LDL Cholesterol
Unit mmol / L
Overall Analytical Principle Method Calculated
Number of Subjects 25
Number of Subjects included in BV estimation 25
Ethinicity Caucasian
Age Mean / Median 29.5
Age Min
Age Max
Age SD 3.6
Number of Males 13
Number of Females 12
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 4
Interval Units Hour
Sampling Times Start Time:
End Time:
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 1.0
Estimates of CVi 8.6
Calculated Confidence Intervals of CVi Lower: 7.50, Upper: 9.91
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 2.4
Calculated Confidence Intervals of Analytical CV Lower: 1.77, Upper: 3.71
Measurand Mean 3.33
Measurand Min
Measurand Max
Measurand SD