Included in meta analysis


Hammond J, Wentz P, Statland BE, Phillips JC and Winkel P, 1976, Clin Chim Acta, 73, 347-52 , Daily variation of lipids and hormones in sera of healthy subjects


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Serum
Measurand Cholesterol
Unit mg / dL
Overall Analytical Principle Method Spectrophotometry; Enzymatic
Number of Subjects 14
Number of Subjects included in BV estimation 14
Ethinicity Caucasian
Age Mean / Median
Age Min 23.0
Age Max 40.0
Age SD
Number of Males 8
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Week
Sampling Times Start Time: 8
End Time: 8:30
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 2.0
Estimates of CVi 4.8
Calculated Confidence Intervals of CVi Lower: 4.06, Upper: 5.82
Estimates of CVg 19.5
Calculated Confidence Intervals of CVg Lower: 14.21, Upper: 30.85
Analytical CV 1.9
Calculated Confidence Intervals of Analytical CV Lower: 1.65, Upper: 2.24
Measurand Mean 213.0
Measurand Min
Measurand Max
Measurand SD