Sexual-hormone-binding-globulin (SHBG)

Reference

Reference
Jayagopal V, Kilpatrick ES, Jennings PE, Hepburn DA and Atkin SL, 2003, J Clin Endocrinol Metab, 88(4), 1528-33 , The Biological Variation of Testosterone and Sex Hormone-Binding Globulin (SHBG) in Polycystic Ovarian Syndrome: Implications for SHBG as a Surrogate Marker of Insulin Resistance

Originally from this reference: J Clin Endocrinol Metab, Jayagopal V, Kilpatrick ES, Jennings PE, Hepburn DA and Atkin SL, 2003


ID: 0404

Scoring

Total Score

C8,12,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
11. ANOVA B
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,12,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Sexual-hormone-binding-globulin (SHBG)
Unit nmol / L
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 12
Number of Subjects included in BV estimation
Ethinicity Caucasian
Age Mean / Median 28.0
Age Min 18.0
Age Max 31.0
Age SD
Number of Males
Number of Females 12
State of Well Being Non-healthy (excl pregnant)
Study Duration Length 40
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time: 8
End Time: 9
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 19.4
Calculated Confidence Intervals of CVi Lower: 17.12, Upper: 22.39
Estimates of CVg 79.3
Calculated Confidence Intervals of CVg Lower: 56.70, Upper: 131.15
Analytical CV 1.3
Calculated Confidence Intervals of Analytical CV Lower: 1.15, Upper: 1.49
Measurand Mean 22.87
Measurand Min 17.81
Measurand Max 27.93
Measurand SD

Coding

Parameter Score
Healthy Population false
Adult Population true
Weekly Samplings true
Reviewed true
Published true
Gender for Meta-Analysis Females
Snomed CT
NPU
LOINC
Comment
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